24-Hour Crisis Hotline: (877)SAFEGBC or (877)723-3422 Mental Health & Substance Abuse Issues

6502 Nursery Drive, Suite 100
Victoria, TX 77904

Alzheimers Disease and other Cognitive Disorders
Basic Information
Introduction & Causes of Cognitive DisordersDementiaAlzheimer's DiseaseOther Cognitive DisordersDementia Coping Skills & Behavior ManagementTraumatic Brain Injury (TBI)Conclusion and Resources
More InformationLatest News
Proton Pump Inhibitor Use Ups Pneumonia Risk in DementiaVitamin E, Selenium Supplements Won't Curb Men's Dementia RiskDizzy Spells in Middle-Age Tied to Dementia Risk LaterFive Million American Seniors Now Living With Alzheimer'sStudy: Gene Test Needed Before Using Alzheimer's Drug 'Off-Label'Annual Death Toll From Alzheimer's Nearly Doubles in 15 YearsImmune Disorders Such as MS, Psoriasis May Be Tied to Dementia RiskIs Need for More Sleep a Sign of Pending Dementia?Unhealthy in Middle Age, Dementia in Old Age?HRT Won't Lower Women's Alzheimer's Risk, Study FindsReview Links Albuminuria to Cognitive Impairment, DementiaCan Air Pollution Heighten Alzheimer's Risk?Bilingual People May Have an Edge Against Alzheimer'sBusy Minds May Be Better at Fighting DementiaDementia May Be Exacerbated by Hospital-Related DeliriumLink Seen Between Concussions and Alzheimer'sContinuing Warfarin Protective After Diagnosis of DementiaDoes Living Near Major Roads Boost Dementia Risk?Caregiver Phone Support Ups Use of Community ResourcesAntipsychotic Drugs May Up Risk of Early Death in Alzheimer's PatientsIs Dementia in Older Women Tied to 20-Year Rate of Weight Loss?Better Sleep May Signal Recovery From Brain Injuryβ-Blockers May Not Be Appropriate for Dementia PatientsTest Predicting Alzheimer's Would Be Welcome, Survey FindsWhether Statins Cut Alzheimer's Risk May Depend on Gender, RaceBeta Blockers May Not Be Best Heart Drugs for Dementia PatientsAlzheimer's Patients' Use of Painkilling Patches Cause for ConcernYoung Adults With Head Trauma May Have Higher Risk of Jail TimePotentially Unsafe Med Scripts Up for Dual Users With DementiaScans Show Changes in Some Soldiers With Mild Brain InjuriesAlzheimer's Protein Plaques May Also Harm the HeartCan Occupational Therapy Slow Alzheimer's Decline?Fewer Americans Suffering From Dementia, Study FindsPoor Sense of Smell May Signal Alzheimer's RiskSome Elderly With Alzheimer's Brain Plaques Stay SharpMRI May Help ID Lewy Body Dementia Versus Alzheimer'sBrain Scans May Improve Dementia Diagnosis, TreatmentHealth Tip: Recognizing Traumatic Brain InjuryCould Loneliness Be an Early Sign of Alzheimer's?Resistance Training Beneficial in Mild Cognitive ImpairmentStudy Links Disasters to DementiaAnimal Study Hints at Gene Therapy's Possible Promise for Alzheimer'sHigh Blood Pressure May Hike Dementia RiskStudy Finds Fault With ICU Treatment of Dementia PatientsWomen's Memory Advantage Might Skew Alzheimer's DiagnosisDeep Brain Stimulation May Improve TBI SymptomsCan Brain 'Pacemaker' Improve Lives of Head Trauma Patients?Antidepressant Might Prevent Depression Following Brain Injury9/11 Responders May Be at Higher Risk for Early DementiaEven a Little Exercise May Help Stave Off Dementia
Questions and AnswersLinks
Related Topics

Continuing Warfarin Protective After Diagnosis of Dementia

HealthDay News
Updated: Jan 6th 2017

new article illustration

FRIDAY, Jan. 6, 2017 (HealthDay News) -- For veterans receiving warfarin for nonvalvular atrial fibrillation, continuing warfarin after a diagnosis of dementia is associated with a protective effect in prevention of stroke and mortality, according to a study published online Dec. 30 in the Journal of the American Geriatrics Society.

Ariela R. Orkaby, M.D., from the Veterans Affairs Boston Healthcare System, and colleagues conducted a retrospective cohort study involving 2,572 veterans aged 65 years and older who had been receiving warfarin for nonvalvular atrial fibrillation for six months or more and were newly diagnosed with dementia. Participants were followed for up to four years.

The researchers found that 405 individuals (16 percent) persisted on warfarin therapy after a diagnosis of dementia. Warfarin had a significant protective effect in prevention of ischemic stroke, major bleeding, and all-cause mortality (hazard ratios [HRs], 0.64 [95 percent confidence interval (CI), 0.46 to 0.89; P = 0.008], 0.72 [95 percent CI, 0.55 to 0.94; P = 0.02], and 0.66 [95 percent CI, 0.55 to 0.79; P < 0.001], respectively). The protective effect of continuing warfarin persisted in prevention of stroke and mortality in propensity-matched analyses (HRs, 0.74 [95 percent CI, 0.54 to 0.996; P = 0.047] and 0.72 [95 percent CI, 0.60 to 0.87; P < 0.001], respectively); there was no statistically significant decrease in the risk of major bleeding (HR, 0.78 [95 percent CI, 0.61 to 1.01; P = 0.06]).

"Discontinuing warfarin after a diagnosis of dementia is associated with a significant increase in stroke and mortality," the authors write.

Full Text (subscription or payment may be required)