|Basic InformationMore InformationTestsLatest News|Studies Question Link Between Mom's Antidepressant Use, Autism in KidsMortality Up With Depression Just Before Breast Cancer DiagnosisDepressive Disorders Up With Antimuscarinics for OABTrauma as a Teen May Boost Depression Risk Around MenopauseBlood Test Promising for ID of Early Depression, SchizophreniaBlood Test Might Someday Distinguish Early Depression, SchizophreniaHold That Pose: Yoga May Ease Tough DepressionDepression May Hasten Death in Years After Heart DiagnosisAntidepressant Efficacy Varies for Depressive Symptom ClustersDepressed Psoriasis Patients at Higher Risk of Psoriatic ArthritisInternet-Based CBT Effective for Depressive SymptomsCan Depression Up Odds for Arthritis Linked to Psoriasis?Postpartum Depressive Symptoms Fell in 2004 to 2012Hey Fellas, Depression Can Strike New Dads, TooDepression Often Untreated in Dialysis PatientsGDM Found to Increase Risk for Postpartum DepressionPostpartum Depression Affects New Dads, TooPanic Disorder May Up Odds of Depression Rx Side EffectsSometimes the Holidays Aren't Always JollyPilots Suffer Depression, Suicidal Thoughts at Fairly High RatesMore Than 1 in 10 Pilots Suffer From Depression, Survey FindsSelf-Care Tools Cut Depression in AMD, Diabetic RetinopathyClinical Antecedents of Adolescent-Onset MDD IdentifiedAge-Related Cataract Linked to Depressive SymptomsDepression, Suicide Ideation Prevalent in Medical Students2 Out of 3 Depressed Teens Gain Lasting Benefits From TherapyAntidepressants + Exercise Beneficial in Late-Life DepressionDepressed Women Less Likely to Get Best Breast Cancer Care: StudyDepression on the Rise Among U.S. Teens, Especially GirlsMemantine + Sertraline Effective for Major Depressive DisorderDepressive Symptoms Linked to Functional Status in CADHigh Rate of Antidepressant Use After CancerResearchers Find Antidepressant Bupropion Crosses PlacentaSome Antihypertensives Linked to Depression, Bipolar RiskMom-to-Be's Antidepressant Use May Be Tied to Speech Issues in ChildDepression Can Fuel Heart Disease in Midlife Women: StudyDepression Common in Patients With Chronic Angina'The Pill' May Raise Depression RiskFacebook Bullying Can Cause DepressionStroke Survivors Often Struggle With DepressionMany Cases of Depression in Adults Not Being TreatedMany Depressed Adults Not Getting Treatment: StudyMajor Depressive Disorder Ups Acute MI Risk in HIV-InfectedPostpartum Depression Can Be ID'd During Infant HospitalizationDepression Common After Time Spent in ICUStudy Finds Links Between Chronic Pain, Depression in CouplesDepression Can Stalk Families Through GenerationsScientists Spot 15 Regions of Human DNA Linked to DepressionBehavioral Activation Therapy Viable Option in DepressionCould New 'Talk Therapy' Cut Cost of Treating Depression?Questions and AnswersLinks
Panic Disorder May Up Odds of Depression Rx Side Effects
Updated: Jan 9th 2017
MONDAY, Jan. 9, 2017 (HealthDay News) -- For patients with chronic depression, comorbid panic disorder is associated with increased likelihood of side effects during treatment, according to a study published online Jan. 3 in the Journal of Clinical Psychiatry.
Stewart A. Shankman, Ph.D., from the University of Illinois at Chicago, and colleagues examined the specificity of side effects among 808 chronically depressed individuals receiving antidepressants according to a predetermined algorithm for 12 weeks. Side effects (specific side effects and indicators of side effect burden) were assessed every two weeks.
The researchers found that lifetime diagnosis of panic disorder at baseline correlated with increased odds of gastrointestinal, cardiac, neurological, and genitourinary side effects during treatment (odds ratios, 1.6, 1.8, 2.6, and 3.0, respectively). For patients with versus those without panic disorder, increases in side effect frequency, intensity, and impairment over time were more strongly correlated with increases in depressive symptoms. There was no correlation for social phobia or generalized anxiety disorder with these effects.
"Potentially due to heightened interoceptive awareness of changes in their body, chronically depressed individuals with panic disorder may be at greater risk than those without panic disorder for antidepressant side effects and to experience a worsening of depressive symptoms as a result of these side effects over time," the authors write.
Several authors disclosed financial ties to the biopharmaceutical industry.
Full Text (subscription or payment may be required)
This article: Copyright © 2017 HealthDay. All rights reserved.