|Basic InformationMore InformationTestsLatest News|Antidepressants Used by 12.7 Percent of Those Age ≥12 in U.S.U.S. Antidepressant Use Jumps 65 Percent in 15 YearsSmoking During Pregnancy Up Among Women With DepressionDepression After Coronary Artery Disease Diagnosis Ups Death RiskYoga May Help Ease DepressionToo Soon to Widely Recommend Ketamine for DepressionLonger Estrogen Exposure May Protect Against DepressionEstrogen May Influence Women's Depression RiskLosing Medicaid Tough on People Battling Depression: StudyLink for Maternal Antidepressant, Kids' Brain Health QuestionedAddition of Aripiprazole Ups Major Depressive Disorder RemissionNo Sign That Antidepressants in Pregnancy Harm Kids' Brains: StudyMed Switch Not Always Best Choice With Tough DepressionDepression Contributes to Health Decline Seen in Cancer CaregiversDepression May Worsen Health for Cancer CaregiversElectric Brain Stimulation No Better Than Meds For Depression: StudyDepression Inversely Linked to Body Composition in TeensReview: Depression Screening As Inpatient Important, FeasibleDepression Can Slow Hospital Patients' Recovery: StudyAntidepressants During Pregnancy Safe for Baby: StudyChronic Pain Common in Adults With Depression, AnxietyWhat You Need to Know About AntidepressantsAPA: Internet-Based CBT Can Be Helpful in DepressionCan Online Treatment Replace Your Therapist?Depression Often a Precursor to Falls in Elderly PeopleOverweight in Childhood May Up Lifetime Risk of DepressionHeavy Kids Face Triple the Odds for Depression in AdulthoodObesity, Sex Predict Remission for Antidepressant MedicationsGender Differences in Depression Tend to Appear About Age 12Depression's Gender Gap Shows Up in Pre-Teen YearsStudies Question Link Between Mom's Antidepressant Use, Autism in KidsMortality Up With Depression Just Before Breast Cancer DiagnosisDepressive Disorders Up With Antimuscarinics for OABTrauma as a Teen May Boost Depression Risk Around MenopauseBlood Test Promising for ID of Early Depression, SchizophreniaBlood Test Might Someday Distinguish Early Depression, SchizophreniaHold That Pose: Yoga May Ease Tough DepressionDepression May Hasten Death in Years After Heart DiagnosisAntidepressant Efficacy Varies for Depressive Symptom ClustersDepressed Psoriasis Patients at Higher Risk of Psoriatic ArthritisInternet-Based CBT Effective for Depressive SymptomsCan Depression Up Odds for Arthritis Linked to Psoriasis?Postpartum Depressive Symptoms Fell in 2004 to 2012Hey Fellas, Depression Can Strike New Dads, TooDepression Often Untreated in Dialysis PatientsGDM Found to Increase Risk for Postpartum DepressionPostpartum Depression Affects New Dads, TooPanic Disorder May Up Odds of Depression Rx Side EffectsSometimes the Holidays Aren't Always JollyPilots Suffer Depression, Suicidal Thoughts at Fairly High RatesQuestions and AnswersLinks
Panic Disorder May Up Odds of Depression Rx Side Effects
Updated: Jan 9th 2017
MONDAY, Jan. 9, 2017 (HealthDay News) -- For patients with chronic depression, comorbid panic disorder is associated with increased likelihood of side effects during treatment, according to a study published online Jan. 3 in the Journal of Clinical Psychiatry.
Stewart A. Shankman, Ph.D., from the University of Illinois at Chicago, and colleagues examined the specificity of side effects among 808 chronically depressed individuals receiving antidepressants according to a predetermined algorithm for 12 weeks. Side effects (specific side effects and indicators of side effect burden) were assessed every two weeks.
The researchers found that lifetime diagnosis of panic disorder at baseline correlated with increased odds of gastrointestinal, cardiac, neurological, and genitourinary side effects during treatment (odds ratios, 1.6, 1.8, 2.6, and 3.0, respectively). For patients with versus those without panic disorder, increases in side effect frequency, intensity, and impairment over time were more strongly correlated with increases in depressive symptoms. There was no correlation for social phobia or generalized anxiety disorder with these effects.
"Potentially due to heightened interoceptive awareness of changes in their body, chronically depressed individuals with panic disorder may be at greater risk than those without panic disorder for antidepressant side effects and to experience a worsening of depressive symptoms as a result of these side effects over time," the authors write.
Several authors disclosed financial ties to the biopharmaceutical industry.
Full Text (subscription or payment may be required)
This article: Copyright © 2017 HealthDay. All rights reserved.