24-Hour Crisis Hotline: (877)SAFEGBC or (877)723-3422 Mental Health & Substance Abuse Issues

6502 Nursery Drive, Suite 100
Victoria, TX 77904
(361)575-0611
(800)421-8825

Alzheimers Disease and other Cognitive Disorders
Resources
Basic Information
Introduction & Causes of Cognitive DisordersDementiaAlzheimer's DiseaseOther Cognitive DisordersDementia Coping Skills & Behavior ManagementTraumatic Brain Injury (TBI)Conclusion and Resources
More InformationLatest News
Magnesium Levels Tied to Dementia RiskIs Dementia Declining Among Older Americans?Intracranial Pressure Monitoring No Benefit in Pediatric TBIGender-Specific High-Risk 'Window' Seen in Alzheimer'sWomen at Risk for Alzheimer's Face Critical 10-Year Window, Study SaysDo Fewer Nightly Dreams Mean Higher Dementia Risk in Seniors?Dementia Care: A Huge Financial Burden for U.S. FamiliesPopular Heartburn Drugs Don't Raise Risk of Alzheimer's: StudyFamilies Shoulder Majority of Costs Related to Dementia CareMidlife Vascular Risk Factors Tied to Increased Risk of DementiaBlood Pressure Fluctuations Tied to Dementia Risk in StudyMidlife Behaviors May Affect Your Dementia RiskTraveling With Dementia: Tips for Family CaregiversHigher Risk of Dementia Seen in Those Hailing From 'Stroke Belt'Health Tip: Alzheimer's Affects SleepIncreased Dementia Risk With Hearing Loss in Older AdultsNoninvasive Brain Test May Pinpoint Type of DementiaTargeting 9 Risk Factors Could Prevent 1 in 3 Dementia Cases: StudyAAIC: Rx + Training Shows Benefit in Advanced Alzheimer'sAAIC: Alzheimer Biomarkers Up With Sleep Disordered BreathingDozens of Potential Alzheimer's Meds in the PipelineSpecial Training Plus Medication Might Help People With Advanced Alzheimer'sOne Social Hour a Week Can Help Someone With DementiaSleep Problems: An Early Warning Sign of Alzheimer's?Severe Head Injury May Raise Dementia Risk Years LaterPPIs Not Found to Raise Risk of Alzheimer's DiseasePopular Heartburn Meds Don't Raise Alzheimer's Risk: StudyLifestyle Changes Might Prevent or Slow DementiaSevere Headaches Plague Vets With Traumatic Brain InjuriesSticky Brain 'Plaques' Implicated in Alzheimer's Again'Making the Best of It': Families Face the Heavy Burden of Alzheimer'sCognitive Decline Linked to Visual Field VariabilityAlzheimer's Deaths Jump 55 Percent: CDCLife Expectancy Slighter Shorter With Parkinson's, DementiaLow Body Mass Index Not Risk Factor for Alzheimer's DiseaseThin People Not More Prone to Alzheimer's, Study FindsWives, Daughters Shoulder Most of Alzheimer's Care BurdenGene Mutation May Speed Alzheimer's DeclineSilent Seizures May Contribute to Alzheimer's Pathology'Silent' Seizures Tied to Alzheimer's SymptomsPsychiatric Scars of Wartime Brain Injury May Linger for YearsMany Patients With Alzheimer's Disease Discontinue AChEIsMicrovascular Endothelial Dysfunction Can Predict DementiaAntipsychotic Medication Use Can Be Reduced in Dementia PatientsPast Psychiatric Disorders Do Not Raise Risk of Alzheimer's DiseasePast Psychiatric Ills Don't Raise Alzheimer's Risk: StudyXanax, Valium May Boost Pneumonia Risk in Alzheimer's PatientsSGA Prescribing Higher for Veterans With PTSD/DementiaDrug Tied to Dementia Risk Overprescribed to Seniors: StudyProton Pump Inhibitor Use Ups Pneumonia Risk in Dementia
Questions and AnswersLinks
Related Topics

Proton Pump Inhibitor Use Ups Pneumonia Risk in Dementia


HealthDay News
Updated: Mar 30th 2017

new article illustration

THURSDAY, March 30, 2017 (HealthDay News) -- For patients with dementia, proton pump inhibitor (PPI) use is associated with increased risk of pneumonia, according to a study published online March 21 in the Journal of the American Geriatrics Society.

Sai-Wai Ho, M.D., from the Chung Shan Medical University in Taichung, China, and colleagues conducted a retrospective cohort study involving 786 patients with dementia with new PPI usage and 786 matched patients with dementia without PPI usage.

The researchers found that patients with PPI usage had higher incidence of pneumonia (adjusted hazard ratio, 1.89). Independent risk factors for pneumonia included age, male gender, underlying cerebrovascular disease, chronic pulmonary disease, congestive heart failure, diabetes mellitus, and antipsychotic use (adjusted hazard ratios, 1.05, 1.57, 1.30, 1.39, 1.54, 1.54, and 1.29, respectively). Pneumonia risk was decreased with usage of cholinesterase inhibitors and histamine receptor-2 antagonists.

"PPI usage in dementia patients is associated with an 89 percent increased risk of pneumonia," the authors write.

Abstract
Full Text (subscription or payment may be required)