24-Hour Crisis Hotline: (877)SAFEGBC or (877)723-3422 Mental Health & Substance Abuse Issues

6502 Nursery Drive, Suite 100
Victoria, TX 77904

Medical Disorders
Basic InformationLookupsLatest News
For Many With Mild Asthma, Popular Rx May Not Work: StudyCleaner Air Linked to Lower Asthma Rates in KidsCholesterol Levels Improving Among U.S. KidsPool Chemicals Harm Thousands Every SummerAre Diets High in Processed Foods a Recipe for Obesity?Lupus Takes Bigger Toll on Longevity for BlacksScientists Spot Unexpected Player in FibromyalgiaAnthrax Is a Risk on Every ContinentAHA News: More Clues to the Genetics Behind an Inherited Cholesterol DisorderSuspect Your Child Has an Ear Infection? There May Soon Be an App for ThatLyme Disease Now a Threat in City Parks Health Tip: Treating a Charley HorseMore Back-to-Back Heat Waves Will Come With Climate ChangeParents, Here's How to Protect Your Child During Measles OutbreaksAHA News: Dangerous Blood Clots May Be the Latest Risk From 'Bad' CholesterolAre You Running Short on Iron?1 in 4 American Workers Struggles With Back PainInjured Lungs Can Be Regenerated for Transplant: StudyKeeping Your Summer Fun on Sound FootingMore Active Lupus Linked to Childhood EventsSigns of Rheumatoid Arthritis Can Show Up Long Before DiagnosisSummer Is Tough for Asthma SufferersHepatitis A Infections Soaring: CDCIs the County You Call Home a Potential Measles Hotspot?'Zap' Ear Clip May Ease A-FibTake Steps to Prevent a StrokeDoes Removing Your Appendix Put You at Risk for Parkinson's?Potentially Blinding Shingles of the Eye on the RisePsoriasis, Mental Ills Can Go Hand in HandAfter Concussions, Some Ex-Athletes Show Key Marker for Brain Disease: StudyWindow for Safe Use of Clot-Buster Widens for Stroke PatientsAn Antibiotic Alternative? Using a Virus to Fight BacteriaDo Adults Need a Measles Booster Shot?Military Tourniquets Might Save Kids' Lives During School ShootingsWell Water's Spillover Effect: Heart Damage?AHA News: Helping Asian-Americans Fight Their Hidden Heart RisksSunscreen Chemicals Enter Bloodstream at Potentially Unsafe Levels: Study'Ringing in the Ears' May Drive Some to the Brink of SuicideBlood Test Might Diagnose Chronic Fatigue SyndromeAsthma Inhalers Incorrectly Used by Most Kids in StudyDevice Helps Doctors Select Lungs for TransplantBenlysta Approved for Children With LupusIn a World First, Drone Delivers Kidney for TransplantHigh Measles Rates Mean Kids, Adults Need Proper Vaccination: CDCParents, Protect Your Kids as Measles Outbreaks SpreadWork Stress, Poor Sleep, High Blood Pressure a Deadly TrioFor Obese People, Commuting by Car Can Be a Killer: StudyHealth Tip: Tick RemovalHalf of Older Dialysis Patients Die Within a Year, Study FindsIs Peanut Allergy 'Immunotherapy' Causing More Harm Than Good?
Questions and AnswersLinks
Related Topics


Kidney Failure Patients Face Higher Risk of Cancer Death

HealthDay News
by By Steven ReinbergHealthDay Reporter
Updated: Feb 14th 2019

new article illustration

THURSDAY, Feb. 14, 2019 (HealthDay News) -- Patients with kidney failure who are on dialysis or have received a transplant have a sharply higher risk of dying from cancer, Australian researchers report.

In fact, compared with people who don't have kidney failure, they have more than double the odds of cancer death. The odds are particularly high among patients aged 20 to 34, for whom the risk is 11 times higher, the researchers reported.

"We need to be aware of the risks of cancer and look for better ways to care for these people in addition to their kidney disease," said lead researcher Eric Au, a doctoral candidate at the University of Sydney.

Kidney failure affects thousands of Americans. Of the more than 660,000 being treated for the problem, 468,000 are on dialysis and more than 193,000 have had a transplant, according to the National Kidney Foundation.

Each year more than 100,000 Americans are diagnosed with kidney failure.

In this study, the investigators found that among dialysis patients, cancer deaths were mostly from cancers that began before dialysis. Cancer deaths among transplant patients, however, were mostly from cancers that started after the transplant.

Patients on dialysis seem to have higher odds of dying from cancers related to kidney failure, such as kidney cancer and multiple myeloma, Au said.

"These patients may have developed kidney failure at the same time as the cancer or as a result of the cancer," he added.

But patients with kidney transplants have increased rates of dying from cancers such as non-Hodgkin lymphoma and melanoma, Au said.

"These cancers may be related to the long-term immunosuppressive medications, which patients need to take after their kidney transplants," he noted.

For the study, Au and his team collected data on nearly 53,000 patients who started dialysis and almost 17,000 who received kidney transplants between 1980 and 2014. The researchers compared these patients with people without kidney disease.

Over 10 years, about 6 percent of the dialysis patients died of cancer, as did nearly 5 percent of those who had a transplant. Kidney patients were nearly three times more likely to die from cancer than those without kidney disease, the study found. And the risk was particularly high among women.

Among transplant patients, most cancers related to immune deficiency and infection, and the study authors explained that this may be the result of long-term use of immunosuppressive drugs required to prevent rejection of a transplant organ.

"We need further studies to look at the reasons for this and how we can reduce these people's risks of cancer, such as better screening of people at risk of cancer and better treatment of those with cancer," Au said.

Dr. Maria DeVita, chief of nephrology at Lenox Hill Hospital in New York City, reviewed the study findings.

DeVita said that while the overall quality of life of patients with kidney failure is better with a transplant, and dialysis is life-sustaining, this study is a reminder that a transplant is not a cure.

"We must remain vigilant in our cancer surveillance of this vulnerable population," she said. "Additional work will need to be done to determine the mechanisms and guide prevention."

The report was published online Feb. 14 in the Journal of the American Society of Nephrology.

More information

To learn more about kidney disease, visit the National Kidney Foundation.