24-Hour Crisis Hotline: (877)SAFEGBC or (877)723-3422 Mental Health & Substance Abuse Issues

6502 Nursery Drive, Suite 100
Victoria, TX 77904
(361)575-0611
(800)421-8825

Medical Disorders
Resources
Basic InformationLookupsLatest News
Tiny Self-Guided Robot Navigates Through the HeartE. Coli Outbreak Tied to Ground Beef Expands to 10 StatesHealth Tip: AppendectomyFatal Medical Emergencies on the Rise Worldwide: StudyAsthma Myths That Can Hurt YouCan Obesity Shrink Your Brain?Health Tip: Understanding Kidney StonesEverything You Need to Know About Lyme DiseaseThe Benefits of an Anti-Inflammatory DietYou Can Cut Your Odds for an Aortic AneurysmAHA News: Evidence Grows for an HPV-Heart Disease ConnectionStrict Blood Pressure Limits for Kids Tied to Heart Health LaterAlmost Half of Young Asthma Patients Misuse Inhalers'Superbugs' Hang Out on Hospital PatientsHealth Tip: Understanding the Tetanus ShotHealth Tip: Earache Home CareListeria Outbreak Linked to Deli Meats, Cheeses in 4 StatesWill You Get Fat? Genetic Test May TellFood Allergies Can Strike at Any AgeWhy a Knee Replacement Can Go BadExperimental Blood Thinner May Help Prevent Stroke, Without the Bleeding RiskBuyer Beware When Purchasing Medical Test StripsEgg Allergy? Don't Let That Stop You From Getting VaccinatedGene Therapy Might Prove a Cure for 'Bubble Boy' DiseaseTwo Lives Saved in Rare 'Paired' Liver DonationYour Life Span May Be Foretold in Your Heart BeatsHealth Tip: Stopping NosebleedsKids Can Get UTIs, TooIs a New Remedy for Body Odor on the Horizon?Why More Patients Are Surviving an AneurysmCommon Diabetes Drug May Also Shield Kidneys, HeartIsraeli Team Announces First 3D-Printed Heart Using Human Cells'Added Sugars' Label on Foods Could Save Many LivesCPAP Brings Longer Life for Obese People With Sleep Apnea: StudyYoung Athletes Need to Be Sidelined After Bout of MonoPre-Cut Melons at Kroger, Walmart, Other Stores May Carry SalmonellaCDC Says Ground Beef Is Source of E. coli Outbreak, Cases Rise to 109AHA News: Is Yoga Heart-Healthy? It's No Stretch to See Benefits, Science SuggestsFDA Orders Label Warning on Alcohol Use With 'Female Viagra'Could Treating Gut Bacteria Help Ease Autism Symptoms?Hospital Privacy Curtains Could Be Breeding Ground for GermsItchy Skin Common Alongside Kidney DiseaseMany Misdiagnosed With MSVehicle Exhaust Drives Millions of New Asthma Cases AnnuallyNFL Retirees Help Scientists Develop Early Test for Brain Condition CTEMigraine Pain Linked to Raised Suicide RiskMore Time Spent in Sports, Faster Healing From ConcussionHealth Tip: Thermometer OptionsStill No Source as E. Coli Outbreak Grows to 96 Cases Across 5 States: CDCClimate Change Could Worsen Sneezin' Season
Questions and AnswersLinks
Related Topics

Diabetes

Ancestry Matters When Seeking Matched Bone Marrow Donors

HealthDay News
by -- Robert Preidt
Updated: Mar 27th 2019

new article illustration

WEDNESDAY, March 27, 2019 (HealthDay News) -- The chances of finding an unrelated bone marrow donor are higher for U.S. patients of European descent than for those of non-European descent, a new study finds.

A bone marrow transplant can sometimes help people with life-threatening blood cancers by replacing the patient's cells with healthy ones from a donor. A brother or sister with the same genetic markers as the recipient is the ideal donor.

For patients without a suitable sibling donor, a transplant from a matched unrelated donor is typically the next best option.

In the new study, researchers looked at just over 1,300 blood cancer patients at Memorial Sloan Kettering Cancer Center, in New York City, who sought a fully matched bone marrow donor between 2005 and 2017.

While 67 percent of patients with European ancestry received a matched transplant from an unrelated donor, the rate was only 33 percent for non-Europeans, including Asians, white Hispanics and Africans. Those of African descent had the lowest rate.

But not all Europeans had equal success: 41 percent from southern Europe had a fully matched donor, compared to between 64 percent and 77 percent of others, according to the study published online March 27 in the journal Blood Advances.

Most who did not have a full match either received a partial match (17 percent of all patients) or a cord blood transplant (24 percent), according to the study. Four percent of patients did not receive a transplant -- the majority of these patients were of African descent.

"We have identified tremendous racial and ethnic disparity in transplant access," study author Juliet Barker said in a journal news release. "What's more, it has been thought by some that if you just increase the number of registered adult donors that it would resolve this problem, but it hasn't."

Barker, director of the Cord Blood Transplant Program at Memorial Sloan Kettering, said the findings show the importance of efforts to improve outcomes of alternative donor transplantation, including the use of unrelated donor cord blood.

Although experts knew that non-European patients have trouble finding a match, the difficulty for patients with origins in southern Europe hasn't been widely appreciated, Barker said.

Transplant centers have the technology to quickly gauge a patient's chances for a matched donor and should abandon futile adult donor searches and donor drives if chances are poor, she said. "This is more and more important as our population increasingly becomes more diverse," Barker concluded.

More information

The National Marrow Donor Program has more on bone marrow transplant.