24-Hour Crisis Hotline: (877)SAFEGBC or (877)723-3422 Mental Health & Substance Abuse Issues

6502 Nursery Drive, Suite 100
Victoria, TX 77904
(361)575-0611
(800)421-8825
Fax: (361)578-5500

Medical Disorders
Resources
Basic InformationLookupsLatest News
Are Disinfectants Putting Nurses at Risk of COPD?Fat Collects in Lungs, Raising Asthma RiskDrug Limits Damage of Brain InjuryMore Patients With Heart Disease Die at Home Than in HospitalYour Noisy Knees May Be Trying to Tell You SomethingHealth Tip: 10 Ways to Reduce Injury RiskIs That Statin Doing You Any Good?Surgery Helps Tough-to-Treat Acid RefluxBrain Damage From Concussion Evident a Year LaterFor Kids With Genetic Condition, Statins May Be LifesaversNext-Gen Artificial Pancreas Boosts Blood Sugar ControlAHA News: Lowering Blood Pressure May Prevent New Brain Lesions in Older PeopleBladder Drug Can Cause Eye Damage: StudyGood News, Bad News on Concussions in High School SportsSteroid Shots for Painful Joints May Make Matters WorseHealth Tip: Broken Toe CareSleep Apnea Linked to Diabetic Eye DiseaseChildhood Risk Factors Can Predict Adult ObesityHealth Tip: Gum Disease Risk FactorsPut Safety First When Planning to Pack Food-to-GoA Parent's Guide to Managing Kids' Asthma During the FallWhat Foods Are Most Likely to Cause Acne Breakouts?Vision Problems Strike More Than 2 Billion GloballyLight Smoking Causes More Lung Damage Than Once Suspected: StudyHealth Tip: Choking First AidBy Mid-Century, Heat Waves Could Cover Far Bigger AreasGet Vaccinated Before Flu Takes Hold: CDCClose to 1,300 Cases of Vaping-Linked Illness Now IdentifiedMore Years of Football, Higher Odds for Brain Disease LaterPain Relief: When to Use Cold, When to Use HeatAHA News: High Triglycerides Caused a Diet Change – at Age 10Humans May Possess Ability to Regrow CartilageHealth Tip: Recognizing Bedbug Bites'Smartphone Slouching' More Serious Than It SoundsAHA News: What's Your Sense of Purpose? The Answer May Affect Your HealthDeep Brain Stimulation May Relieve Ringing in the Ears: StudyWhat Are the Risks of Pain Relief Alternatives to Opioids?Many ICU Admissions May Be Preventable, Large Study SuggestsCause of Paralyzing Illness in Kids Remains ElusiveFlu Season Is Coming: Here's How to Protect YourselfSinus Infections: What You Need to KnowFewer Teeth, Higher Risk of Heart Disease?Fungal Invasion May Drive Some Pancreatic CancersHealth Tip: Lowering Your Resting Heart RateYour Washer Might Be Breeding Drug-Resistant GermsCan Your Eating Habits Keep Alzheimer's at Bay?Prescription Opioids Linked to Poor Outcomes in Kidney PatientsCases of Serious Vaping-Linked Lung Injury Now Top 1,000Organic Chicken Less Likely to Harbor a Dangerous 'Superbug'Running the Numbers on High Blood Pressure
Questions and AnswersLinks
Related Topics

Diabetes

Israeli Team Announces First 3D-Printed Heart Using Human Cells

HealthDay News
by -- Robert Preidt
Updated: Apr 15th 2019

new article illustration

MONDAY, April 15, 2019 (HealthDay News) -- The world's first complete 3D printer-generated heart, made using the patient's own cells and materials, has been created in a lab.

Until now, success has been limited to printing only simple tissues without blood vessels.

"This is the first time anyone anywhere has successfully engineered and printed an entire heart replete with cells, blood vessels, ventricles and chambers," said team leader Tal Dvir.

The printer-generated heart is only about a third the size of an actual human heart -- and it doesn't actually work. But it's a groundbreaking step toward engineering customized organs that can be transplanted with less risk of rejection.

"This heart is made from human cells and patient-specific biological materials," said Dvir, a researcher at the Sagol Center for Regenerative Biotechnology at Tel Aviv University in Israel. "In our process these materials serve as the bio-inks, substances made of sugars and proteins that can be used for 3D printing of complex tissue models."

Dvir noted that scientists have managed to print a 3D structure of a heart before, but not with cells or blood vessels. "Our results demonstrate the potential of our approach for engineering personalized tissue and organ replacement in the future," he said in a university news release.

The research was published online April 15 in the journal Advanced Science.

Heart disease is the leading cause of death in the United States. A transplant is the only treatment available to patients with end-stage heart failure, but there is a severe shortage of heart donors.

That means there's an urgent need to develop new ways to regenerate a diseased heart, according to the researchers.

The use of biological materials from a patient is key to successful engineering of tissues and organs, Dvir explained. The compatibility of engineered materials is key to eliminating rejection risk.

"Ideally, the biomaterial should possess the same biochemical, mechanical and topographical properties of the patient's own tissues," Dvir noted. "Here, we can report a simple approach to 3D-printed thick, vascularized and perfusable cardiac tissues that completely match the immunological, cellular, biochemical and anatomical properties of the patient."

While the 3D-printed heart is about the size of a rabbit's heart, the same technology can be used to print a normal-sized one, he said.

The next step is culturing printed hearts in the lab and "teaching them to behave" like hearts, Dvir added. Then, researchers plan to transplant the 3D-printed heart into lab animals.

"We need to develop the printed heart further," Dvir said. "The cells need to form a pumping ability; they can currently contract, but we need them to work together. Our hope is that we will succeed and prove our method's efficacy and usefulness."

Dvir looks to the future with optimism.

"Maybe, in 10 years, there will be organ printers in the finest hospitals around the world, and these procedures will be conducted routinely," he said.

More information

The U.S. National Heart, Lung, and Blood Institute has more on heart failure.