24-Hour Crisis Hotline: (877)SAFEGBC or (877)723-3422 Mental Health & Substance Abuse Issues

6502 Nursery Drive, Suite 100
Victoria, TX 77904
Fax: (361)578-5500

Basic InformationLatest News
Lost Pregnancies, Diabetes May Be LinkedType 2 Diabetes Linked to Worse Mental Outcomes After StrokeSleep Apnea Tied to Raised Diabetes Risk in Black AmericansHeart Attacks, Strokes Are Declining Among People With DiabetesCould Your Contact Lenses Track, Treat Your Diabetes?AHA News: Managing Diabetes Risk in Hispanic, Asian CommunitiesObesity Is Biggest Type 2 Diabetes Risk FactorAHA News: Understanding the Risky Combination of Diabetes and the CoronavirusWhy Is Coronavirus a Bigger Worry for People With Diabetes?What People With Type 1 Diabetes Need to Know About COVID-19Family Ties Help Young Adults With Type 1 Diabetes FlourishPatch Pump Device Could Offer Cheaper Insulin DeliveryCan AI Predict Who Will Develop Diabetes?Blood Sugar Control May Aid Stroke Recovery in Diabetes PatientsBacteria May Be a Player in Diabetes Among Very ObeseNew Tool Helps Muslims With Diabetes Manage Blood Sugar During Ramadan FastWant to Help Keep Diabetes at Bay? Brush & FlossDiabetes Among U.S. Young, Especially Asians, Continues to ClimbDrug Duo Speeds Regeneration of Key Cells Lost in DiabetesMedicare Could Save Billions If Allowed to Negotiate Insulin PricesAt the Barbershop, a Trim -- and a Diabetes ScreeningCertain Diabetes Meds May Lower Gout Risk, TooBig Advances Made Against Diabetes in 2019CDC Study Breaks Down Diabetes Risk for Hispanic, Asian SubgroupsFDA Authorizes Marketing of Automated Insulin Dosing ControllerDo Processed Foods Up Your Type 2 Diabetes Risk?Changing Timing, Frequency of Meals May Help With Diabetes'Diabetes Burnout' Is Real, Here's How to CopeAs Diabetes Costs Soar, Many Turn to Black Market for HelpFDA Testing Levels of Carcinogen in Diabetes Drug MetforminMom-to-Be's Diabetes May Up Odds of Heart Disease in Her KidsPrediabetes Now Common Among Teens, Young AdultsHeart Attack at 44 Helped Her Realize Diabetes' DangersDiabetes Tougher on Women's HeartsDiabetes Technology Often Priced Out of ReachSupplements Don't Prevent Kidney Disease in Type 2 DiabeticsWhy Are Insulin Prices Still So High for U.S. Patients?Health Tip: Snacks for People With DiabetesHigh-Tech Pacifier Might Monitor Baby's Blood SugarThe Exercise Effect and PrediabetesNext-Gen Artificial Pancreas Boosts Blood Sugar ControlHurricanes Raise Death Risk for Older Diabetics, Even Years LaterYou've Lost the Weight -- Now Keep It Off to Keep Diabetes at BayCould a Pill Replace Insulin Shots?High-Fiber Diet Tied to Lower Heart Risk in Diabetes PatientsJust a Little Weight Loss Can Put Diabetes Into RemissionAffordable Care Act Insured Millions of Uninsured DiabeticsOlder Diabetics May Be Getting Too Much InsulinIt Takes Less Weight to Trigger Diabetes in Minorities Than WhitesFDA OKs New Pill for Type 2 Diabetes
Related Topics

Medical Disorders

FDA Approves First Needle-Free 'Rescue' Drug for Low Blood Sugar Episodes

HealthDay News
by By E.J. Mundell
HealthDay Reporter
Updated: Jul 25th 2019

new article illustration

THURSDAY, July 25, 2019 (HealthDay News) -- In what could prove to be a real advance for Americans with diabetes, the U.S. Food and Drug Administration on Wednesday gave the nod to a needle-free method of helping people recover from an episode of dangerous low blood sugar.

The new formulation, called Baqsimi, contains the rescue medication glucagon, but is instead given as a nasally inhaled powder, the FDA said.

"Until now, people suffering from a severe hypoglycemic episode had to be treated with a glucagon injection that first had to be mixed in a several-step process," explained Dr. Janet Woodcock, who directs the FDA's Center for Drug Evaluation and Research.

Baqsimi "may simplify the process, which can be critical during an episode," she said in an agency news release.

One diabetes expert agreed.

The new drug's approval is "a great boon for people with diabetes at risk for low blood glucose [hypoglycemia], as well as for their families and their health care providers," said Dr. Minisha Sood. She's an endocrinologist at Lenox Hill Hospital in New York City.

Sood noted that very often, a diabetic person is incapacitated by hypoglycemia -- meaning that a friend, family member or other bystander must administer injected glucagon.

That means "training friends and family of patients" on how to inject the drug intramuscularly, which can be a real "limitation," she said.

Having a more "straightforward" option of administering glucagon "is a game-changer when it comes to treating severe hypoglycemia outside of a hospital or doctor's office," Sood said. "I look forward to using this for my patients."

As the FDA explained, "severe hypoglycemia occurs when a patient's blood sugar levels fall to a level where he or she becomes confused or unconscious or suffers from other symptoms that require assistance from another person to treat. Typically, severe hypoglycemia occurs in people with diabetes who are using insulin treatment."

Baqsimi will come in a single-use dispenser easily administered to deliver glucagon-containing powder into the nose. The drug "increases blood sugar levels in the body by stimulating the liver to release stored glucose into the bloodstream," the FDA said.

Wednesday's approval was based on findings from two studies involving 83 and 70 adults with diabetes. Baqsimi was found to work as well as injected glucagon to raise blood sugar levels.

Similar results were found in a study involving 48 children with type 1 diabetes, the FDA added.

Baqsimi, made by Eli Lilly and Co., does have some restrictions. According to the FDA, it shouldn't be used by people with a rare condition known as pheochromocytoma, a tumor of the adrenal gland, or people with a pancreatic tumor known as an insulinoma.

People with known allergies to glucagon shouldn't take Baqsimi, nor should people who've been fasting for a long period, or those with chronic forms of hypoglycemia.

Side effects of Baqsimi were similar to those of injected glucagon, the FDA said.

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases offers more about low blood sugar, including how to prevent it.