24-Hour Crisis Hotline: (877)SAFEGBC or (877)723-3422 Mental Health & Substance Abuse Issues

6502 Nursery Drive, Suite 100
Victoria, TX 77904
(361)575-0611
(800)421-8825
Fax: (361)578-5500

Alzheimers Disease and other Cognitive Disorders
Resources
Basic Information
Introduction & Causes of Cognitive DisordersDementiaAlzheimer's DiseaseOther Cognitive DisordersDementia Coping Skills & Behavior ManagementTraumatic Brain Injury (TBI)Conclusion and Resources
More InformationLatest News
Fall Risk Rises Even in Alzheimer's Early StagesPTSD May Be Tied to Greater Dementia RiskNew Research Links Another Gene to Alzheimer's RiskIs Rural Appalachia a Hotspot for Alzheimer's?Why Are Dementia Patients Getting Risky Psychiatric Drugs?Get Dizzy When Standing Up? It Could Be Risk Factor for DementiaCan Seniors Handle Results of Alzheimer's Risk Tests?More Education May Slow Start of Early-Onset Alzheimer'sUnder 50 and Overweight? Your Odds for Dementia Later May RiseBlood Test Heralds New Era in Alzheimer's Diagnosis9/11 First Responders Have Higher Odds for Alzheimer's: StudyCould the Flu Shot Lower Your Risk for Alzheimer's?Will Your Brain Stay Sharp Into Your 90s? Certain Factors Are KeyResearchers Zero in on Alzheimer's Disease Risk FactorsMany Americans With Dementia Live in Homes With GunsBrain's Iron Stores May Be Key to Alzheimer'sHormones May Explain Greater Prevalence of Alzheimer's in WomenMiddle-Age Obesity Linked to Higher Odds for DementiaCould Crohn's, Colitis Raise Dementia Risk?5 Healthy Steps to Lower Your Odds for Alzheimer'sCOVID-19 Brings New Challenges to Alzheimer's CaregivingAlzheimer's Gene Linked to Severe COVID-19 RiskHealthier Heart, Better Brain in Old AgeAHA News: Hearing Loss and the Connection to Alzheimer's Disease, DementiaBrain Plaques Signal Alzheimer's Even Before Other Symptoms Emerge: StudyCertain Gene Might Help Shield At-Risk People From Alzheimer'sHow to Connect With Nursing Home Patients in QuarantineHow to Ease Loved Ones With Alzheimer's Through the PandemicCaring for Dementia Patient During Pandemic? Try These Stress-Busting TipsDirty Air Might Raise Your Odds for DementiaRecovery From Mild Brain Trauma Takes Longer Than Expected: StudyCould Sleep Apnea Put You at Risk for Alzheimer's?Daily Aspirin Won't Stop Dementia, Study FindsStudy Ties Brain Inflammation to Several Types of DementiaHeart Drug Combos Might Also Lower Your Dementia Risk: StudyU.S. Primary Care Docs Unprepared for Surge in Alzheimer's CasesMaria Shriver Sounds the Alarm on Women and Alzheimer'sTraumatic Brain Injuries Raise Risk of Psychiatric Ills in SoldiersGrowing Up in U.S. 'Stroke Belt' Bad for the Brain Later in LifeTwo Experimental Drugs Disappoint With Inherited Alzheimer'sGene Variant Ups Dementia Risk in Parkinson's Patients: StudyGene Variation May Protect Against Alzheimer's: StudyWhen Dementia Harms Speech, Native Language MattersEven 1 Night's Bad Sleep Can Raise Levels of a Brain 'Marker' for Alzheimer'sAHA News: Worried About Dementia? Check This Blood Pressure NumberStudy Might Point Alzheimer's Research in Whole New DirectionMore Doubt That Plaques in the Brain Cause Alzheimer'sObesity in Middle Age Could Raise Odds for Alzheimer's LaterCan Air Pollution Take a Toll on Your Memory?Animal Study Offers Hope for Treating Traumatic Brain Injuries
Questions and AnswersLinks
Related Topics

Down Syndrome Carries Raised Risk of Dementia by 55

HealthDay News
by -- Robert Preidt
Updated: Nov 4th 2019

new article illustration

MONDAY, Nov. 4, 2019 (HealthDay News) -- Most people with Down syndrome have dementia by age 55, a new study shows.

People with Down syndrome are born with an extra copy of chromosome 21, which often results in developmental disabilities. Surviving to middle age used to be rare, with many dying young due to heart problems associated with the syndrome, the researchers noted.

While treatment advances now enable people with Down syndrome to live longer, healthier lives, they're at increased risk for dementia. And they are likely to be diagnosed at younger ages than other people.

The researchers said that by age 40, the brains of nearly all adults with Down syndrome have signs of dementia, according to autopsies.

In this study, University of Wisconsin-Madison researchers analyzed Medicaid claims data on 3,000 people with Down syndrome, aged 21 and older, in Wisconsin.

The results showed that 3 in 5 people with Down syndrome will be diagnosed with Alzheimer's disease and other types of dementia by age 55. In comparison, people without Down syndrome are rarely diagnosed with dementia before age 65.

"We found [among claims data] that if you started without dementia, as time goes on, your likelihood of diagnosis increases every year," said study senior author Lauren Bishop, a researcher at the UW-Madison Waisman Center and professor in the School of Social Work.

"Your probability of having any dementia is 61% at age 55," she said in a university news release.

It's likely that similar results would be found in other states, according to the study published Oct. 28 in the journal JAMA Neurology.

"Having a number is so important when conveying the importance to policymakers. We can tell them that by age 55, 3 in 5 people with Down syndrome have dementia. It's clear and actionable," said study lead author Eric Rubenstein, a postdoctoral researcher at the Waisman Center.

Along with improving community support for people with Down syndrome, the findings could assist families in planning for their loved ones with Down syndrome -- for example, by enrolling them early in memory care centers, the researchers suggested.

"Whether it's through case managers or group homes or some living assistance or job coaches, as a society we need to support vulnerable people. This is especially important for people with Down syndrome throughout their life course," Bishop said.

More information

The U.S. National Institute of Child Health and Human Development has more on Down syndrome.