24-Hour Crisis Hotline: (877)SAFEGBC or (877)723-3422 Mental Health & Substance Abuse Issues

6502 Nursery Drive, Suite 100
Victoria, TX 77904
(361)575-0611
(800)421-8825
Fax: (361)578-5500

Medical Disorders
Resources
Basic InformationLookupsLatest News
AHA News: Could Fish Oil Fight Inflammation?One Boy's Battle Back From Mysterious Polio-Like IllnessHealth Tip: Advice on Home Wound CareOver 40% of Antibiotics Could Be 'Inappropriately' PrescribedRural Seniors Hurt by Lack of Medical SpecialistsHealth Tip: Understanding Muscle SpasmsBlack Patients May Not Gain Heart Benefit From Low-Dose AspirinIs Pot Use a Heart Risk After Surgery?E. Coli Outbreak Spurs Packaged Salad WarningHealth Tip: Should I Get a Cholesterol Test?Are Superbugs Making Themselves at Home in Your Makeup Bag?Sometimes, Aspirin May Be Enough to Ease MigrainesDangers of 'Superbug' Germs Greater Than BelievedAdditives to E-Cigarettes May Be Upping Health DangersMany Kids Traveling Overseas Aren't Vaccinated Against MeaslesVirtual Doc Visits Suffice for Many With Neurological DisordersBPA Levels in Humans Are Underestimated: StudyCleaner Air Quickly Brings Big Health Benefits, Study FindsAll 50 States Now Reporting Cases of Severe Vaping-Linked Lung Injury3 Drugs for Severe Epileptic Seizures Are Equally Effective: StudyStudy Casts Doubt on Use of Common Heart Failure Drugs'Mobile Stroke Units' Help Rush Treatment to PatientsDistracted by Their Smartphones, Pedestrians Are Landing in the ERVaping May Have Triggered Lung Illness Typically Only Seen in MetalworkersMore Than 100 E. Coli Illnesses Now Linked to Romaine LettuceLow-Dose Aspirin Might Cut Cancer Risk, Especially for Overweight PeopleEspecially in the Young, Cholesterol Is No Friend to the HeartAre E-Scooters a Quick Ticket to the ER?Uncontrolled Asthma a Danger to Pregnant Women, BabiesHealth Tip: Common Causes of Knee PainSome Cities' Smog Can Ruin Your VacationParkinson's Treatment Has Unexpected Side EffectHeart Attack at 44 Helped Her Realize Diabetes' DangersCleaner Teeth, Healthier Heart?Obesity Might Weaken Some Drugs' Effectiveness Against AFibHow to Prevent Holiday HeadachesAir Pollution May Up Glaucoma RiskHealth Tip: Causes of Stomach UlcersHealth Tip: Treating ShinglesLeg Pain Could Spell Peripheral Artery Disease for SomeEven in Small Doses, Air Pollution Harms Older AmericansDon't Let Allergies Spoil Your HolidaysGot Chronic Heartburn? Easy Does It During the Thanksgiving FeastAHA News: Flu Prevention Strategies Beyond Getting a Shot and Washing Your HandsUltrasound Treatment Might Ease Parkinson's TremorsPopular Heartburn Drugs May Up Odds of Stomach BugGunshot Wounds Have Long-Term Health Consequences: StudyU.S. Poison Centers Field More Calls About Psychoactive Substances: StudyMore E. coli Illnesses Linked to Tainted Romaine LettuceFDA Approves First System to Insert Ear Tubes Under Local Anesthesia
Questions and AnswersLinks
Related Topics

Diabetes

Testosterone Supplements Double Men's Odds for Blood Clots: Study

HealthDay News
by By Dennis Thompson
HealthDay Reporter
Updated: Nov 12th 2019

new article illustration

TUESDAY, Nov. 12, 2019 (HealthDay News) -- Testosterone therapy appears to double a man's risk of suffering a potentially life-threatening blood clot, a new study warns.

Men had twice the risk for a deep vein blood clot if they'd been receiving testosterone during the previous six months, researchers reported in the Nov. 11 online edition of JAMA Internal Medicine.

The increased risk occurred whether or not a man had the low-testosterone condition known as hypogonadism, but appeared to be more pronounced in middle-aged men than in seniors, the findings showed.

These findings should cause men to think twice about asking for testosterone treatments to battle normal symptoms of aging, said lead author Rob Walker, a graduate research assistant at the University of Minnesota School of Public Health, in Minneapolis.

"If a potential patient reads this and maybe is seeking out testosterone therapy for some kind of common symptoms, like weight gain or sexual function, maybe they should seek out behavioral changes or lifestyle changes that will improve their health without a prescription," Walker said.

The "low-T" fad caused testosterone prescriptions to soar early in the 21st century, increasing more than 300% between 2001 and 2013, the study authors said in background notes.

The fad faded in 2014, after the U.S. Food and Drug Administration warned that testosterone therapy increases a man's risk of heart attack and stroke.

Still, more than 1 million U.S. men over 30 received testosterone therapy in 2016, the researchers noted. Evidence suggests it's still being prescribed to some who don't suffer hypogonadism, a condition in which the body isn't producing enough of the male hormone.

To further investigate the risk of testosterone treatment, Walker and his team analyzed insurance claims for nearly 40,000 men filed between 2011 and 2017.

The investigators focused on men who experienced either deep vein thrombosis or pulmonary embolism. Pulmonary embolism occurs when a deep vein clot breaks free and travels into the lungs, blocking some or all of their blood supply.

Men without a low-testosterone condition who took the hormone had 2.3 times the risk of developing a deep vein clot within six months, the results showed. Men diagnosed with hypogonadism had 2 times the risk.

The results also indicated that risk might be even greater in middle-aged men taking testosterone to battle aging, although those findings were not statistically significant, Walker said.

"In men without hypogonadism, men under 65 almost had a tripling of risk versus men 65 years and older, whose risk was only about 1.5 times greater," he said.

Testosterone poses this risk because it "revs up the consistency of the clotting factors in the blood," said Dr. Umesh Gidwani, an associate professor of cardiology, critical care and pulmonology at the Icahn School of Medicine at Mount Sinai in New York City.

The hormone increases red blood cell count, which thickens blood and makes it flow more sluggishly, Gidwani said. Testosterone also amps up the action of platelets, the blood cells responsible for forming clots.

The study "seems to suggest it would be safer to refrain from testosterone use in patients who do not have hypogonadism," Gidwani said.

Walker agreed, adding that men who must receive testosterone therapy due to hypogonadism should be closely monitored for blood clots.

More information

The American Heart Association has more about venous thromboembolism.