24-Hour Crisis Hotline: (877)SAFEGBC or (877)723-3422 Mental Health & Substance Abuse Issues

6502 Nursery Drive, Suite 100
Victoria, TX 77904
(361)575-0611
Fax: (361)578-5500
Regular Hours: M-Fri 8am - 5pm
Every 3rd Thurs of the Month - Extended Hours Until 7 pm

Alzheimers Disease and other Cognitive Disorders
Resources
Basic Information
Introduction & Causes of Cognitive DisordersDementiaAlzheimer's DiseaseOther Cognitive DisordersDementia Coping Skills & Behavior ManagementTraumatic Brain Injury (TBI)Conclusion and Resources
More InformationLatest News
Life Span After Alzheimer's Diagnosis: What Factors Matter MostLots of Napping Could Raise a Senior's Odds for Alzheimer'sIs It 'Pre-Alzheimer's' or Normal Aging? Poll Finds Many Americans UnclearAmazon Tribes May Have Lowest Rate of Dementia in the WorldMore Evidence That Education May Protect Against DementiaAHA News: These Three Risk Factors May Have the Biggest Impact on Dementia CasesAHA News: Traumatic Brain Injury May Raise Veterans' Long-Term Stroke RiskMore Years Playing Hockey, Higher Odds for CTE Linked to Head InjuryEarly Menopause May Raise a Woman's Odds for DementiaPandemic Caused Rise in Deaths of Alzheimer's PatientsStaying Fit May Keep Alzheimer's at BayConcussion's Impact on Memory, Thinking May Linger More Than a YearBrain Injuries May Be Driving Higher Death Rate for U.S. VeteransHints That Viagra-Like Drugs Might Help Prevent DementiaAHA News: Statistics Report Offers Snapshot of the Nation's Brain Health – And a Guide to Protecting ItKeeping Weight Stable Could Help Save Your BrainMedicare Proposes to Only Cover Alzheimer's Drug Aduhelm for Use in Clinical TrialsAduhelm: Will Medicare Cover the Controversial Alzheimer's Drug?More U.S. Seniors, Especially Women, Are Retaining Healthy Brains: StudyMaker Cuts Price of Controversial New Alzheimer's Drug in HalfCertain Meds Raise Odds for Delirium After SurgeryCould Viagra Help Prevent Alzheimer's?Clearing Out Clutter Might Not Help People With DementiaLifetime Spent With Epilepsy Ages the Brain, Study FindsHigh Heart Rate Linked to Dementia Risk'Mild Cognitive Impairment' in Older Age Often Disappears, Study FindsMore Years Playing Football, More Brain Lesions on MRI: StudyReminder Apps on Smartphones May Help in Early DementiaNeurologists' Group Issues Guidance to Families on Controversial Alzheimer's DrugTrial Begins of Nasal Vaccine for Alzheimer's DiseaseAlzheimer's Diagnosis May Come With Big Cost to Social LifeMany People May Be Eating Their Way to DementiaCould Estrogen Help Shield Women's Brains From Alzheimer's?Purrfect Pal: Robotic Cats May Help People With DementiaRight Amount of Sleep May Be Important in Early Alzheimer'sAHA News: Hearing Loss and the Link to DementiaDepression in Early Life May Up Dementia Risk LaterScientists Untangle Why Diabetes Might Raise Alzheimer's RiskTracking Key Protein Helps Predict Outcomes in TBI PatientsMIND Diet May Guard Against Alzheimer'sSigns of Early Alzheimer's May Be Spotted in Brain StemCould Cholesterol Help Drive Alzheimer's Disease?Common Eye Conditions Tied to Higher Risk for DementiaMultigenerational Study Finds Links Between ADHD, Dementia RiskMost Alzheimer's Patients Wouldn't Have Qualified for Controversial Drug's Trial: StudyCould Traffic Noise Raise Your Odds for Dementia?AHA News: What Are Researchers Doing to Stop Dementia?A Mentally Challenging Job Could Help Ward Off DementiaDirty Air, Higher Dementia Risk?An ALS Drug Shows Early Promise Against Alzheimer's
Questions and AnswersLinks
Related Topics

Depression in Early Life May Up Dementia Risk Later

HealthDay News
by Steven Reinberg
Updated: Oct 6th 2021

new article illustration

WEDNESDAY, Oct. 6, 2021 (HealthDay News) -- Happy young adults may be somewhat protected from dementia, but the reverse may be true, too: If you're a depressed young adult, your odds for dementia rise, a new study suggests.

"Generally, we found that the greater the depressive symptoms, the lower the cognition and the faster the rates of decline," researcher Willa Brenowitz said.

"Older adults estimated to have moderate or high depressive symptoms in early adulthood were found to experience a drop in cognition over 10 years," added Brenowitz, of the University of California, San Francisco's Department of Psychiatry and Behavioral Sciences.

The researchers developed a statistical model to predict the average arc of depression among 15,000 participants ages 20 to 89. They found that in a group of about 6,000 older adults, the odds of cognitive impairment were 73% higher for those who had symptoms of depression in early adulthood, and 43% higher for those with symptoms of depression in later life.

"Several mechanisms explain how depression might increase dementia risk," Brenowitz said in a university news release. "Among them is that hyperactivity of the central stress response system increases production of the stress hormones glucocorticoids, leading to damage of the hippocampus, the part of the brain essential for forming, organizing and storing new memories."

Other studies have tied depression with shrinking of the hippocampus, and one study has shown faster rates of volume loss in women, she said.

For this study, participants were screened for depression. Moderate or high depressive symptoms were found in 13% of young adults, 26% of midlife adults and 34% of older participants. More than 1,200 participants were diagnosed with cognitive impairment.

With up to 20% of the population suffering from depression during their lifetime, it's important to recognize its role in cognitive, or mental, aging, said researcher Dr. Kristine Yaffe, also of the UCSF Department of Psychiatry and Behavioral Sciences.

"Future work will be needed to confirm these findings, but in the meantime, we should screen and treat depression for many reasons," Yaffe said in the release.

The report was published Sept. 28 in the Journal of Alzheimer's Disease.

More information

The Alzheimer's Association has more on dementia.

SOURCE: University of California, San Francisco, news release, Sept. 28, 2021